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Retro Pinky and the Brain T-Shirt cyndi lauper which includes the characteristic redPinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is a self centered and scheming genius, while Pinky is good natured, but insane. In each episode, Brain devises a new plan to take over the world, and includes Pinky in his plans, which ultimately end in failure. Pinky and the Brain first appeared as a recurring skit on the animated series Animaniacs, and they quickly became the